The effects of meprobamate and pentobarbitone sodium on sleep and motility during sleep: a controlled trial with psychiatric patients.
نویسندگان
چکیده
Meprobamate (2-methyl-2-n-propyl-1, 3-propanediol dicarbamate) was synthesized by Ludwig and Piech (1951). It is an interneuronal blocking agent capable of producing muscular relaxation without affecting respiration or other vital activities (Berger, 1954). The drug produces restful sleep and generalized muscular relaxation (Borrus, 1955). It was decided to test its effect, compared with that of a placebo and pentobarbitone sodium, on motility measured on a bed providing quantified estimates of movement during sleep or recumbency.
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ورودعنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 22 2 شماره
صفحات -
تاریخ انتشار 1959